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Effects of dihydrotestosterone on osteoblast activity in curdlan-administered SKG mice and osteoprogenitor cells in patients with ankylosing spondylitis

BACKGROUND: Ankylosing spondylitis (AS) is characteristically male-predominant, and progressive spinal ankylosis affects male patients more severely; however, the hormonal effects in males with AS are poorly understood. METHODS: In the present study, the regulatory effects of dutasteride, a 5-α redu...

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Publicado en:Arthritis Res Ther
Autores principales: Jo, Sungsin, Lee, Eun-Ju, Nam, Bora, Kang, Juyeon, Lee, Seunghun, Youn, Jeehee, Park, Ye-Soo, Kim, Yong-Gil, Kim, Tae-Hwan
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245802/
https://ncbi.nlm.nih.gov/pubmed/32448352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-020-02217-9
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