Protective Effects of Crocetin on Arsenic Trioxide-Induced Hepatic Injury: Involvement of Suppression in Oxidative Stress and Inflammation Through Activation of Nrf2 Signaling Pathway in Rats

PURPOSE: Arsenic trioxide (ATO) has been shown to induce hepatic injury. Crocetin is a primary constituent of saffron, which has been verified to have antioxidant and anti-inflammatory effects. In the current experiment, we evaluated the efficacy of crocetin against ATO-induced hepatic injury and ex...

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Bibliografiske detaljer
Udgivet i:Drug Des Devel Ther
Main Authors: Liu, Yanshuang, Liang, Yingran, Zheng, Bin, Chu, Li, Ma, Donglai, Wang, Hongfang, Chu, Xi, Zhang, Jianping
Format: Artigo
Sprog:Inglês
Udgivet: Dove 2020
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245440/
https://ncbi.nlm.nih.gov/pubmed/32546959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S247947
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