Magnesium Isoglycyrrhizinate Alleviates Arsenic Trioxide-Induced Cardiotoxicity: Contribution of Nrf2 and TLR4/NF-κB Signaling Pathway

PURPOSE: Magnesium isoglycyrrhizinate (MgIG), a single stereoisomer magnesium salt of glycyrrhizic acid, has beneficial effects on the cardiovascular system through anti-inflammatory, anti-oxidation, and anti-apoptotic actions. However, MgIG has not been shown to provide protection against cardiotox...

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Detalles Bibliográficos
Publicado en:Drug Des Devel Ther
Main Authors: Zheng, Bin, Yang, Yakun, Li, Jinghan, Li, Jing, Zuo, Saijie, Chu, Xi, Xu, Shan, Ma, Donglai, Chu, Li
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2021
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7886103/
https://ncbi.nlm.nih.gov/pubmed/33603344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S296405
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