Insulin enhances renal glucose excretion: relation to insulin sensitivity and sodium-glucose cotransport

INTRODUCTION: Insulin regulates renal glucose production and utilization; both these fluxes are increased in type 2 diabetes (T2D). Whether insulin also controls urinary glucose excretion is not known. METHODS: We applied the pancreatic clamp technique in 12 healthy subjects and 13 T2D subjects. Eac...

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Foilsithe in:BMJ Open Diabetes Res Care
Main Authors: Ferrannini, Ele, Pereira-Moreira, Ricardo, Seghieri, Marta, Rebelos, Eleni, Souza, Aglécio L, Chueire, Valeria B, Arvia, Caterina, Muscelli, Elza
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMJ Publishing Group 2020
Ábhair:
Metabolism
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245398/
https://ncbi.nlm.nih.gov/pubmed/32423964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2020-001178
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