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Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients

Background. Sodium-glucose cotransporter 2 (SGLT2) inhibitors lower glycemia by enhancing urinary glucose excretion. The physiologic response to pharmacologically induced acute or chronic glycosuria has not been investigated in human diabetes. Methods. We evaluated 66 patients with type 2 diabetes (...

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Detalhes bibliográficos
Main Authors: Ferrannini, Ele, Muscelli, Elza, Frascerra, Silvia, Baldi, Simona, Mari, Andrea, Heise, Tim, Broedl, Uli C., Woerle, Hans-Juergen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904627/
https://ncbi.nlm.nih.gov/pubmed/24463454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72227
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