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Metabolic response to sodium-glucose cotransporter 2 inhibition in type 2 diabetic patients

Background. Sodium-glucose cotransporter 2 (SGLT2) inhibitors lower glycemia by enhancing urinary glucose excretion. The physiologic response to pharmacologically induced acute or chronic glycosuria has not been investigated in human diabetes. Methods. We evaluated 66 patients with type 2 diabetes (...

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Autores principales: Ferrannini, Ele, Muscelli, Elza, Frascerra, Silvia, Baldi, Simona, Mari, Andrea, Heise, Tim, Broedl, Uli C., Woerle, Hans-Juergen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3904627/
https://ncbi.nlm.nih.gov/pubmed/24463454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI72227
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