The SrrAB two-component system regulates Staphylococcus aureus pathogenicity through redox sensitive cysteines

Staphylococcus aureus infections can lead to diseases that range from localized skin abscess to life-threatening toxic shock syndrome. The SrrAB two-component system (TCS) is a global regulator of S. aureus virulence and critical for survival under environmental conditions such as hypoxic, oxidative...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Tiwari, Nitija, López-Redondo, Marisa, Miguel-Romero, Laura, Kulhankova, Katarina, Cahill, Michael P., Tran, Phuong M., Kinney, Kyle J., Kilgore, Samuel H., Al-Tameemi, Hassan, Herfst, Christine A., Tuffs, Stephen W., Kirby, John R., Boyd, Jeffery M., McCormick, John K., Salgado-Pabón, Wilmara, Marina, Alberto, Schlievert, Patrick M., Fuentes, Ernesto J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7245129/
https://ncbi.nlm.nih.gov/pubmed/32354997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1921307117
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