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Citarinostat and Momelotinib co-target HDAC6 and JAK2/STAT3 in lymphoid malignant cell lines: a potential new therapeutic combination

Histone deacetylase (HDAC) inhibitors represent an encouraging class of antitumor drugs. HDAC inhibitors induce a series of molecular and biological responses and minimal toxicity to normal cells. Citarinostat (Acy-241) is a second generation, orally administered, HDAC6-selective inhibitor. Momeloti...

詳細記述

保存先:
書誌詳細
出版年:Apoptosis
主要な著者: Cosenza, Maria, Civallero, Monica, Marcheselli, Luigi, Sacchi, Stefano, Pozzi, Samantha
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244621/
https://ncbi.nlm.nih.gov/pubmed/32394008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-020-01607-3
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