The histone deacetylase inhibitor romidepsin synergizes with lenalidomide and enhances tumor cell death in T-cell lymphoma cell lines

We investigated the cytotoxic interactions of romidepsin, a histone deacetylase inhibitor, and lenalidomide, an immunomodulatory agent, in a T-cell lymphoma preclinical model. Hut-78 and Karpas-299 cells were treated with romidepsin and lenalidomide alone and in combination. The interaction between...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Ther
Main Authors: Cosenza, Maria, Civallero, Monica, Fiorcari, Stefania, Pozzi, Samantha, Marcheselli, Luigi, Bari, Alessia, Ferri, Paola, Sacchi, Stefano
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5079402/
https://ncbi.nlm.nih.gov/pubmed/27657380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2016.1219820
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