The E3 ubiquitin ligase TRIM7 suppressed hepatocellular carcinoma progression by directly targeting Src protein

Aberrant Src kinase activity is known to be involved in a variety of human malignancies, whereas the regulatory mechanism of Src has not been completely clarified. Here, we demonstrated that tripartite motif containing 7 (TRIM7) directly interacted with Src, induced Lys48-linked polyubiquitination o...

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Vydáno v:Cell Death Differ
Hlavní autoři: Zhu, Lihui, Qin, Chengyong, Li, Tao, Ma, Xiaomin, Qiu, Yumin, Lin, Yueke, Ma, Dapeng, Qin, Zhenzhi, Sun, Caiyu, Shen, Xuecheng, Zhao, Yunxue, Han, Lihui
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244582/
https://ncbi.nlm.nih.gov/pubmed/31802035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0464-9
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