Proteasome-dependent degradation of Smad7 is critical for lung cancer metastasis

Lung cancer is one of the cancers with highest morbidity and mortality rates and the metastasis of lung cancer is a leading cause of death. Mechanisms of lung cancer metastasis are yet to be fully understood. Herein, we demonstrate that mice deficient for REGγ, a proteasome activator, exhibited a si...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Tong, Lu, Shen, Shihui, Huang, Quan, Fu, Junjiang, Wang, Tianzhen, Pan, Linian, Zhang, Pei, Chen, Geng, Huang, Tingmei, Li, Ke, Liu, Qingwu, Xie, Shaofang, Yang, Xiao, Moses, Robb E., Li, Xiaotao, Li, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244558/
https://ncbi.nlm.nih.gov/pubmed/31767934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-019-0459-6
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