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N(6)-methyladenosine regulates glycolysis of cancer cells through PDK4
Studies on biological functions of N(6)-methyladenosine (m(6)A) modification in mRNA have sprung up in recent years. We find m(6)A can positively regulate the glycolysis of cancer cells. Specifically, m(6)A-sequencing and functional studies confirm that pyruvate dehydrogenase kinase 4 (PDK4) is invo...
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| Publié dans: | Nat Commun |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244544/ https://ncbi.nlm.nih.gov/pubmed/32444598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16306-5 |
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