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N(6)-methyladenosine regulates glycolysis of cancer cells through PDK4

Studies on biological functions of N(6)-methyladenosine (m(6)A) modification in mRNA have sprung up in recent years. We find m(6)A can positively regulate the glycolysis of cancer cells. Specifically, m(6)A-sequencing and functional studies confirm that pyruvate dehydrogenase kinase 4 (PDK4) is invo...

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書目詳細資料
發表在:Nat Commun
Main Authors: Li, Zihan, Peng, Yanxi, Li, Jiexin, Chen, Zhuojia, Chen, Feng, Tu, Jian, Lin, Shuibin, Wang, Hongsheng
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244544/
https://ncbi.nlm.nih.gov/pubmed/32444598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16306-5
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