Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells

Oncogenic transformation impacts cancer cell interactions with their stroma, including through formation of abnormal blood vessels. This influence is often attributed to angiogenic growth factors, either soluble, or associated with tumor cell-derived extracellular vesicles (EVs). Here we examine som...

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Publicat a:Sci Rep
Autors principals: Chennakrishnaiah, Shilpa, Tsering, Thupten, Gregory, Caroline, Tawil, Nadim, Spinelli, Cristiana, Montermini, Laura, Karatzas, Nicolaos, Aprikian, Saro, Choi, Dongsic, Klewes, Ludger, Mai, Sabine, Rak, Janusz
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244541/
https://ncbi.nlm.nih.gov/pubmed/32444772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65640-7
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