Extracellular vesicles from genetically unstable, oncogene-driven cancer cells trigger micronuclei formation in endothelial cells

Oncogenic transformation impacts cancer cell interactions with their stroma, including through formation of abnormal blood vessels. This influence is often attributed to angiogenic growth factors, either soluble, or associated with tumor cell-derived extracellular vesicles (EVs). Here we examine som...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Chennakrishnaiah, Shilpa, Tsering, Thupten, Gregory, Caroline, Tawil, Nadim, Spinelli, Cristiana, Montermini, Laura, Karatzas, Nicolaos, Aprikian, Saro, Choi, Dongsic, Klewes, Ludger, Mai, Sabine, Rak, Janusz
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244541/
https://ncbi.nlm.nih.gov/pubmed/32444772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65640-7
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