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p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators

High rates of glycolysis in cancer cells are a well-established characteristic of many human tumors, providing rapidly proliferating cancer cells with metabolites that can be used as precursors for anabolic pathways. Maintenance of high glycolytic rates depends upon the lactate dehydrogenase–catalyz...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Sci Signal
Main Authors: Birts, Charles N., Banerjee, Arindam, Darley, Matthew, Dunlop, Charles R., Nelson, Sarah, Nijjar, Sharandip K., Parker, Rachel, West, Jonathan, Tavassoli, Ali, Rose-Zerilli, Matthew J.J., Blaydes, Jeremy P.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2020
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244340/
https://ncbi.nlm.nih.gov/pubmed/32371497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau9529
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