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p53 is regulated by aerobic glycolysis in cancer cells by the CtBP family of NADH-dependent transcriptional regulators
High rates of glycolysis in cancer cells are a well-established characteristic of many human tumors, providing rapidly proliferating cancer cells with metabolites that can be used as precursors for anabolic pathways. Maintenance of high glycolytic rates depends upon the lactate dehydrogenase–catalyz...
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| I publikationen: | Sci Signal |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2020
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7244340/ https://ncbi.nlm.nih.gov/pubmed/32371497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aau9529 |
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