Urokinase-Type Plasminogen Activator Protects Cerebral Cortical Neurons from Soluble Aβ-Induced Synaptic Damage

Soluble amyloid β (Aβ)-induced synaptic dysfunction is an early event in the pathogenesis of Alzheimer's disease (AD) that precedes the deposition of insoluble Aβ and correlates with the development of cognitive deficits better than the number of plaques. The mammalian plasminogen activation (P...

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Vydáno v:J Neurosci
Hlavní autoři: Diaz, Ariel, Merino, Paola, Guo, Ji-Dong, Yepes, Manuel A., McCann, Patrick, Katta, Tapasya, Tong, Elise M., Torre, Enrique, Rangaraju, Srikant, Yepes, Manuel
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2020
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244203/
https://ncbi.nlm.nih.gov/pubmed/32332118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2804-19.2020
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