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Urokinase-type plasminogen activator (uPA) promotes ezrin-mediated reorganization of the synaptic cytoskeleton in the ischemic brain

Synaptic repair in the ischemic brain is a complex process that requires reorganization of the actin cytoskeleton. Ezrin, radixin, and moesin (ERM) are a group of evolutionarily conserved proteins that link the plasma membrane to the actin cytoskeleton and act as scaffolds for signaling transduction...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Merino, Paola, Diaz, Ariel, Manrique, Luis Guillermo, Cheng, Lihong, Yepes, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005443/
https://ncbi.nlm.nih.gov/pubmed/29720403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002534
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