Lycopene prevents carcinogen-induced cutaneous tumor by enhancing activation of the Nrf2 pathway through p62-triggered autophagic Keap1 degradation

Biologically active natural products have been used for the chemoprevention of cutaneous tumors. Lycopene is the main active phytochemical in tomatoes. We herein aimed to assess the cancer preventive effects of lycopene and to find potential molecular targets. In chemically-induced cutaneous tumor m...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Wang, Siliang, Wu, Yuan-Yuan, Wang, Xu, Shen, Peiliang, Jia, Qi, Yu, Suyun, Wang, Yuan, Li, Xiaoman, Chen, Wenxing, Wang, Aiyun, Lu, Yin
Format: Artigo
Language:Inglês
Published: Impact Journals 2020
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7244072/
https://ncbi.nlm.nih.gov/pubmed/32365333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.103132
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