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Activation of the Keap1/Nrf2 stress response pathway in autophagic vacuolar myopathies
Nrf2 (nuclear factor [erythroid-derived 2]-like 2; the transcriptional master regulator of the antioxidant stress response) is regulated through interaction with its cytoplasmic inhibitor Keap1 (Kelch-like ECH-associated protein 1), which under basal conditions targets Nrf2 for proteasomal degrad...
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| Publicat a: | Acta Neuropathol Commun |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5088660/ https://ncbi.nlm.nih.gov/pubmed/27799074 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0384-6 |
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