Dynamic Supraspliceosomes Are Assembled on Different Transcripts Regardless of Their Intron Number and Splicing State

Splicing and alternative splicing of pre-mRNA are key sources in the formation of diversity in the human proteome. These processes have a central role in the regulation of the gene expression pathway. Yet, how spliceosomes are assembled on a multi-intronic pre-mRNA is at present not well understood....

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Bibliographic Details
Published in:Front Genet
Main Authors: Sebbag-Sznajder, Naama, Brody, Yehuda, Hochberg-Laufer, Hodaya, Shav-Tal, Yaron, Sperling, Joseph, Sperling, Ruth
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243799/
https://ncbi.nlm.nih.gov/pubmed/32499811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00409
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