Availability of splicing factors in the nucleoplasm can regulate the release of mRNA from the gene after transcription

Gene expression dynamics can be measured in single living cells. Using a detectable transcriptionally active gene in living cells, we previously found that an mRNA undergoing several splicing events was retained at this gene after transcription until completion of mRNA processing. To determine the r...

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Udgivet i:PLoS Genet
Main Authors: Hochberg-Laufer, Hodaya, Neufeld, Noa, Brody, Yehuda, Nadav-Eliyahu, Shani, Ben-Yishay, Rakefet, Shav-Tal, Yaron
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901260/
https://ncbi.nlm.nih.gov/pubmed/31765392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1008459
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