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Evaluation of nCoV-QS (MiCo BioMed) for RT-qPCR detection of SARS-CoV-2 from nasopharyngeal samples using CDC FDA EUA qPCR kit as a gold standard: An example of the need of validation studies

BACKGROUND: Several qPCR kits are available for SARS-CoV-2 diagnosis, mostly lacking of evaluation due to covid19 emergency. OBJECTIVE: We evaluated nCoV-QS (MiCo BioMed) kit using CDC kit as gold standard. RESULTS: We found limitations for nCoV-QS: 1) lower sensitivity 2) lack of RNA quality contro...

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Detalhes bibliográficos
Publicado no:J Clin Virol
Main Authors: Freire-Paspuel, Byron, Vega-Mariño, Patricio, Velez, Alberto, Castillo, Paulina, Cruz, Marilyn, Garcia-Bereguiain, Miguel Angel
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243755/
https://ncbi.nlm.nih.gov/pubmed/32485473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcv.2020.104454
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