Rapid Alterations in Cerebral White Matter Lipid Profiles After Ischemic-Reperfusion Brain Injury in Fetal Sheep as Demonstrated by MALDI-Mass Spectrometry

BACKGROUND: Perinatal ischemia-reperfusion (I/R) injury of cerebral white matter causes long-term cognitive and motor disabilities in children. I/R damages or kills highly metabolic immature oligodendroglia via oxidative stress, excitotoxicity, inflammation, and mitochondrial dysfunction, impairing...

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Vydáno v:Pediatr Dev Pathol
Hlavní autoři: Gallucci, Gina M, Tong, Ming, Chen, Xiaodi, Stonestreet, Barbara S, Lin, Amy, de la Monte, Suzanne M
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243471/
https://ncbi.nlm.nih.gov/pubmed/30683019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1093526619826721
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