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Cigarette Smoke-Induced Alterations in Frontal White Matter Lipid Profiles Demonstrated by MALDI-Imaging Mass Spectrometry: Relevance to Alzheimer’s Disease

BACKGROUND: Meta-analysis has shown that smokers have significantly increased risks for Alzheimer’s disease (AD), and neuroimaging studies showed that smoking alters white matter (WM) structural integrity. OBJECTIVE: Herein, we characterize the effects of cigarette smoke (CS) exposures and withdrawa...

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Detalhes bibliográficos
Publicado no:J Alzheimers Dis
Main Authors: Nunez, Kavin, Kay, Jared, Krotow, Alexander, Tong, Ming, Agarwal, Amit R., Cadenas, Enrique, de la Monte, Suzanne M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575809/
https://ncbi.nlm.nih.gov/pubmed/26836183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-150916
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