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Altered Temporal Lobe White Matter Lipid Ion Profiles in an Experimental Model of Sporadic Alzheimer;s Disease

BACKGROUND: White matter is an early and important yet under-evaluated target of Alzheimer’s disease (AD). Metabolic impairments due to insulin and insulin-like growth factor resistance contribute to white matter degeneration because corresponding signal transduction pathways maintain oligodendrocyt...

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Détails bibliographiques
Publié dans:Mol Cell Neurosci
Auteurs principaux: Tong, Ming, Leão, Raiane, Vimbela, Gina V., Yalcin, Emine B., Kay, Jared, Krotow, Alexander, de la Monte, Suzanne M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5507369/
https://ncbi.nlm.nih.gov/pubmed/28438696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2017.04.010
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