Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca(2+) Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response

Swi-independent 3a and 3b (Sin3a and Sin3b) are paralogous transcriptional coregulators that direct cellular differentiation, survival, and function. Here, we report that mouse Sin3a and Sin3b are coproduced in most pancreatic cells during embryogenesis but become much more enriched in endocrine cel...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Diabetes
Prif Awduron: Yang, Xiaodun, Graff, Sarah M., Heiser, Cody N., Ho, Kung-Hsien, Chen, Bob, Simmons, Alan J., Southard-Smith, Austin N., David, Gregory, Jacobson, David A., Kaverina, Irina, Wright, Christopher V.E., Lau, Ken S., Gu, Guoqiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2020
Pynciau:
Islet Studies
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243292/
https://ncbi.nlm.nih.gov/pubmed/32245798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0721
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