Coregulator Sin3a Promotes Postnatal Murine β-Cell Fitness by Regulating Genes in Ca(2+) Homeostasis, Cell Survival, Vesicle Biosynthesis, Glucose Metabolism, and Stress Response

Swi-independent 3a and 3b (Sin3a and Sin3b) are paralogous transcriptional coregulators that direct cellular differentiation, survival, and function. Here, we report that mouse Sin3a and Sin3b are coproduced in most pancreatic cells during embryogenesis but become much more enriched in endocrine cel...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Yang, Xiaodun, Graff, Sarah M., Heiser, Cody N., Ho, Kung-Hsien, Chen, Bob, Simmons, Alan J., Southard-Smith, Austin N., David, Gregory, Jacobson, David A., Kaverina, Irina, Wright, Christopher V.E., Lau, Ken S., Gu, Guoqiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243292/
https://ncbi.nlm.nih.gov/pubmed/32245798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0721
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