Epigenetic reprogramming sensitizes immunologically silent EBV(+) lymphomas to virus-directed immunotherapy

Despite advances in T-cell immunotherapy against Epstein-Barr virus (EBV)-infected lymphomas that express the full EBV latency III program, a critical barrier has been that most EBV(+) lymphomas express the latency I program, in which the single Epstein-Barr nuclear antigen (EBNA1) is produced. EBNA...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Dalton, Tanner, Doubrovina, Ekaterina, Pankov, Dmitry, Reynolds, Raymond, Scholze, Hanna, Selvakumar, Annamalai, Vizconde, Teresa, Savalia, Bhumesh, Dyomin, Vadim, Weigel, Christoph, Oakes, Christopher C., Alonso, Alicia, Elemento, Olivier, Pan, Heng, Phillip, Jude M., O’Reilly, Richard J., Gewurz, Benjamin E., Cesarman, Ethel, Giulino-Roth, Lisa
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243148/
https://ncbi.nlm.nih.gov/pubmed/32157281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019004126
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