Evaluation of the Anti-Tumor Activity of Small Molecules Targeting Eph/Ephrins in APC (min)/J Mice

The Eph receptors are the largest receptors tyrosine kinases (RTKs) family in humans and together with ephrin ligands constitute a complex cellular communication system often dysregulated in many tumors. The role of the Eph-ephrin system in colorectal cancer (CRC) has been investigated and different...

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Veröffentlicht in:Pharmaceuticals (Basel)
Hauptverfasser: Corrado, Miriam, Giorgio, Carmine, Barocelli, Elisabetta, Marzetti, Giuseppe Vittucci, Cantoni, Anna Maria, Di Lecce, Rosanna, Incerti, Matteo, Castelli, Riccardo, Lodola, Alessio, Tognolini, Massimiliano
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243115/
https://ncbi.nlm.nih.gov/pubmed/32316101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13040069
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