MetaPhat: Detecting and Decomposing Multivariate Associations From Univariate Genome-Wide Association Statistics

BACKGROUND: Multivariate testing tools that integrate multiple genome-wide association studies (GWAS) have become important as the number of phenotypes gathered from study cohorts and biobanks has increased. While these tools have been shown to boost statistical power considerably over univariate te...

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Bibliographic Details
Published in:Front Genet
Main Authors: Lin, Jake, Tabassum, Rubina, Ripatti, Samuli, Pirinen, Matti
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242752/
https://ncbi.nlm.nih.gov/pubmed/32499813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00431
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