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The Use of Computational Approaches in the Discovery and Mechanism Study of Opioid Analgesics
Opioid receptors that belong to class A G protein-coupled receptors (GPCRs) are vital in pain control. In the past few years, published high-resolution crystal structures of opioid receptor laid a solid basis for both experimental and computational studies. Computer-aided drug design (CADD) has been...
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| Publicat a: | Front Chem |
|---|---|
| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Frontiers Media S.A.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7242749/ https://ncbi.nlm.nih.gov/pubmed/32500054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00335 |
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