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Computational Approaches in Preclinical Studies on Drug Discovery and Development

Because undesirable pharmacokinetics and toxicity are significant reasons for the failure of drug development in the costly late stage, it has been widely recognized that drug ADMET properties should be considered as early as possible to reduce failure rates in the clinical phase of drug discovery....

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Библиографические подробности
Опубликовано в: :Front Chem
Главные авторы: Wu, Fengxu, Zhou, Yuquan, Li, Langhui, Shen, Xianhuan, Chen, Ganying, Wang, Xiaoqing, Liang, Xianyang, Tan, Mengyuan, Huang, Zunnan
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517894/
https://ncbi.nlm.nih.gov/pubmed/33062633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00726
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