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Computational Approaches in Preclinical Studies on Drug Discovery and Development

Because undesirable pharmacokinetics and toxicity are significant reasons for the failure of drug development in the costly late stage, it has been widely recognized that drug ADMET properties should be considered as early as possible to reduce failure rates in the clinical phase of drug discovery....

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書目詳細資料
發表在:Front Chem
Main Authors: Wu, Fengxu, Zhou, Yuquan, Li, Langhui, Shen, Xianhuan, Chen, Ganying, Wang, Xiaoqing, Liang, Xianyang, Tan, Mengyuan, Huang, Zunnan
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2020
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7517894/
https://ncbi.nlm.nih.gov/pubmed/33062633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00726
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