Global responses to oxytetracycline treatment in tetracycline-resistant Escherichia coli

We characterized the global transcriptome of Escherichia coli MG1655:: tetA grown in the presence of ½ MIC (14 mg/L) of OTC, and for comparison WT MG1655 strain grown with 1//2 MIC of OTC (0.25 mg/L OTC). 1646 genes changed expression significantly (FDR > 0.05) in the resistant strain, the majori...

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Udgivet i:Sci Rep
Main Authors: Møller, Thea S. B., Liu, Gang, Hartman, Hassan B., Rau, Martin H., Mortensen, Sisse, Thamsborg, Kristian, Johansen, Andreas E., Sommer, Morten O. A., Guardabassi, Luca, Poolman, Mark G., Olsen, John E.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242477/
https://ncbi.nlm.nih.gov/pubmed/32439837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-64995-1
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