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New Structural insights into Kir channel gating from molecular simulations, HDX-MS and functional studies

Inward rectifier potassium (Kir) channels play diverse and important roles in shaping action potentials in biological membranes. An increasing number of diseases are now known to be directly associated with abnormal Kir function. However, the gating of Kir still remains unknown. To increase our unde...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fagnen, Charline, Bannwarth, Ludovic, Oubella, Iman, Forest, Eric, De Zorzi, Rita, de Araujo, Aline, Mhoumadi, Yasmina, Bendahhou, Saïd, Perahia, David, Vénien-Bryan, Catherine
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242327/
https://ncbi.nlm.nih.gov/pubmed/32439887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-65246-z
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