Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help

The inherent molecular complexity of human pathogens requires that mammals evolved an adaptive immune system equipped to handle presentation of non-conventional MHC ligands derived from disease-causing agents, such as HIV-1 envelope (Env) glycoprotein. Here, we report that a CD4(+) T cell repertoire...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Sun, Lina, Paschall, Amy V., Middleton, Dustin R., Ishihara, Mayumi, Ozdilek, Ahmet, Wantuch, Paeton L., Aceil, Javid, Duke, Jeremy A., LaBranche, Celia C., Tiemeyer, Michael, Avci, Fikri Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242320/
https://ncbi.nlm.nih.gov/pubmed/32439962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-16319-0
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