Effects of Sodium–Glucose Co-transporter 2 Inhibition with Empaglifozin on Renal Structure and Function in Non-diabetic Rats with Left Ventricular Dysfunction After Myocardial Infarction

BACKGROUND: The use of sodium–glucose co-transporter 2 inhibitors (SGLT2i) is currently expanding to cardiovascular risk reduction in non-diabetic subjects, but renal (side-)effects are less well studied in this setting. METHODS: Male non-diabetic Sprague Dawley rats underwent permanent coronary art...

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Bibliographic Details
Published in:Cardiovasc Drugs Ther
Main Authors: Yurista, Salva R., Silljé, Herman H. W., van Goor, Harry, Hillebrands, Jan-Luuk, Heerspink, Hiddo J. L., de Menezes Montenegro, Luiz, Oberdorf-Maass, Silke U., de Boer, Rudolf A., Westenbrink, B. Daan
Format: Artigo
Language:Inglês
Published: Springer US 2020
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7242237/
https://ncbi.nlm.nih.gov/pubmed/32185580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-020-06954-6
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