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Gp41-targeted antibodies restore infectivity of a fusion-deficient HIV-1 envelope glycoprotein
The HIV-1 envelope glycoprotein (Env) mediates viral entry via conformational changes associated with binding the cell surface receptor (CD4) and coreceptor (CCR5/CXCR4), resulting in subsequent fusion of the viral and cellular membranes. While the gp120 Env surface subunit has been extensively stud...
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| 出版年: | PLoS Pathog |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7241850/ https://ncbi.nlm.nih.gov/pubmed/32392227 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008577 |
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