Evaluation of Zhenwu Decoction Effects on CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS

This thesis is aimed at shedding light on the effects of the Zhenwu decoction (ZWD) on the activities and mRNA expressions of seven CYP450 isoenzymes. In the first step, we determined the main chemical compounds of ZWD by high-performance liquid chromatography (HPLC). Next, 48 male (SD) rats were ra...

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Udgivet i:Biomed Res Int
Main Authors: Hong, Li-li, Wang, Qian, Zhao, Ya-ting, Zhang, Sheng, Zhang, Kai-qi, Chen, Wei-dong, Peng, Can, Liu, Li, Wang, Hong-song
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240782/
https://ncbi.nlm.nih.gov/pubmed/32461991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4816209
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