Evaluation of Zhenwu Decoction Effects on CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS

This thesis is aimed at shedding light on the effects of the Zhenwu decoction (ZWD) on the activities and mRNA expressions of seven CYP450 isoenzymes. In the first step, we determined the main chemical compounds of ZWD by high-performance liquid chromatography (HPLC). Next, 48 male (SD) rats were ra...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Hong, Li-li, Wang, Qian, Zhao, Ya-ting, Zhang, Sheng, Zhang, Kai-qi, Chen, Wei-dong, Peng, Can, Liu, Li, Wang, Hong-song
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240782/
https://ncbi.nlm.nih.gov/pubmed/32461991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/4816209
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