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Effect of Delaying Treatment on Efficacy of Ciprofloxacin and Levofloxacin in the African Green Monkey Model of Pneumonic Plague

BACKGROUND: Ciprofloxacin and levofloxacin, 2 fluoroquinolone antimicrobials, are ≥90% effective for the treatment of inhalational plague when administered within 2–6 hours of fever onset in African green monkeys (AGM). Based on data in the AGM model, these antimicrobials were approved under the Foo...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Campbell, Joseph L, Fay, Michael P, Lanning, Lynda L, Hewitt, Judith A
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240338/
https://ncbi.nlm.nih.gov/pubmed/32435805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz1234
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