mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice

To date, mRNA-based biologics have mainly been developed for prophylactic and therapeutic vaccination to combat infectious diseases or cancer. In the past years, optimization of the characteristics of in vitro transcribed mRNA has led to significant reduction of the inflammatory responses. Thanks to...

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Publicado en:Mol Ther Nucleic Acids
Autores principales: Van Hoecke, Lien, Verbeke, Rein, De Vlieger, Dorien, Dewitte, Heleen, Roose, Kenny, Van Nevel, Sharon, Krysko, Olga, Bachert, Claus, Schepens, Bert, Lentacker, Ine, Saelens, Xavier
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240188/
https://ncbi.nlm.nih.gov/pubmed/32438313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.04.015
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