mRNA Encoding a Bispecific Single Domain Antibody Construct Protects against Influenza A Virus Infection in Mice

To date, mRNA-based biologics have mainly been developed for prophylactic and therapeutic vaccination to combat infectious diseases or cancer. In the past years, optimization of the characteristics of in vitro transcribed mRNA has led to significant reduction of the inflammatory responses. Thanks to...

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Vydáno v:Mol Ther Nucleic Acids
Hlavní autoři: Van Hoecke, Lien, Verbeke, Rein, De Vlieger, Dorien, Dewitte, Heleen, Roose, Kenny, Van Nevel, Sharon, Krysko, Olga, Bachert, Claus, Schepens, Bert, Lentacker, Ine, Saelens, Xavier
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Gene & Cell Therapy 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240188/
https://ncbi.nlm.nih.gov/pubmed/32438313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2020.04.015
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