Lack of Helios During Neural Development Induces Adult Schizophrenia-Like Behaviors Associated With Aberrant Levels of the TRIF-Recruiter Protein WDFY1

The role of the WDFY1 protein has been studied as a TLR3/4 scaffold/recruiting protein in the immune system and in different oncogenic conditions. However, its function in brain remains poorly understood. We have found that in mice devoid of Helios (He(–/–) mice), a transcription factor specifically...

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Dettagli Bibliografici
Pubblicato in:Front Cell Neurosci
Autori principali: Sancho-Balsells, Anna, Brito, Veronica, Fernández, Belissa, Pardo, Mónica, Straccia, Marco, Ginés, Silvia, Alberch, Jordi, Hernández, Isabel, Arranz, Belén, Canals, Josep M., Giralt, Albert
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Neuroscience
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240114/
https://ncbi.nlm.nih.gov/pubmed/32477064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.00093
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