Functional Properties of Helicobacter pylori VacA Toxin m1 and m2 Variants

Helicobacter pylori colonizes the gastric mucosa and secretes a pore-forming toxin (VacA). Two main types of VacA, m1 and m2, can be distinguished by phylogenetic analysis. Type m1 forms of VacA have been extensively studied, but there has been relatively little study of m2 forms. In this study, we...

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Publicado en:Infect Immun
Autores principales: Caston, Rhonda R., Sierra, Johanna C., Foegeding, Nora J., Truelock, Mandy D., Campbell, Anne M., Frick-Cheng, Arwen E., Bimczok, Diane, Wilson, Keith T., McClain, Mark S., Cover, Timothy L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2020
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240096/
https://ncbi.nlm.nih.gov/pubmed/32284370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00032-20
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