Functional Properties of Helicobacter pylori VacA Toxin m1 and m2 Variants

Helicobacter pylori colonizes the gastric mucosa and secretes a pore-forming toxin (VacA). Two main types of VacA, m1 and m2, can be distinguished by phylogenetic analysis. Type m1 forms of VacA have been extensively studied, but there has been relatively little study of m2 forms. In this study, we...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Caston, Rhonda R., Sierra, Johanna C., Foegeding, Nora J., Truelock, Mandy D., Campbell, Anne M., Frick-Cheng, Arwen E., Bimczok, Diane, Wilson, Keith T., McClain, Mark S., Cover, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240096/
https://ncbi.nlm.nih.gov/pubmed/32284370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00032-20
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