Aging Dampens the Intestinal Innate Immune Response during Severe Clostridioides difficile Infection and Is Associated with Altered Cytokine Levels and Granulocyte Mobilization

Clostridioides (formerly Clostridium) difficile is the most common cause of hospital-acquired infection, and advanced age is a risk factor for C. difficile infection. Disruption of the intestinal microbiota and immune responses contribute to host susceptibility and severity of C. difficile infection...

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Bibliografiska uppgifter
I publikationen:Infect Immun
Huvudupphovsmän: Abernathy-Close, Lisa, Dieterle, Michael G., Vendrov, Kimberly C., Bergin, Ingrid L., Rao, Krishna, Young, Vincent B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Host Response and Inflammation
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240091/
https://ncbi.nlm.nih.gov/pubmed/32284366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00960-19
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