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Identification of Pathogenicity Island Genes Associated with Loss of Type IV Secretion Function during Murine Infection with Helicobacter pylori

Chronic Helicobacter pylori colonization in animal models often leads to downregulation of the type IV secretion system (T4SS), typically by recombination in cagY, which is an essential T4SS gene. However, 17 other cag pathogenicity island (cagPAI) genes, as well as some non-cagPAI genes, are also e...

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Vydáno v:Infect Immun
Hlavní autoři: Hansen, Lori M., Dekalb, Dylan J., Cai, Lucy P., Solnick, Jay V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240090/
https://ncbi.nlm.nih.gov/pubmed/32205402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00801-19
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