CagY-Dependent Regulation of Type IV Secretion in Helicobacter pylori Is Associated with Alterations in Integrin Binding

Strains of Helicobacter pylori that cause ulcer or gastric cancer typically express a type IV secretion system (T4SS) encoded by the cag pathogenicity island (cagPAI). CagY is an ortholog of VirB10 that, unlike other VirB10 orthologs, has a large middle repeat region (MRR) with extensive repetitive...

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Udgivet i:mBio
Main Authors: Skoog, Emma C., Morikis, Vasilios A., Martin, Miriam E., Foster, Greg A., Cai, Lucy P., Hansen, Lori M., Li, Beibei, Gaddy, Jennifer A., Simon, Scott I., Solnick, Jay V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5954226/
https://ncbi.nlm.nih.gov/pubmed/29764950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00717-18
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