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Efficient Nonviral Stable Transgenesis Mediated by Retroviral Integrase

Efficient transgene delivery is critical for genetic manipulation and therapeutic intervention of target cells. Two well-characterized integrative systems have been described that rely on viral and nonviral vectors. However, use of viral vectors for gene therapy has been associated with several safe...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Chiang, Chang-Ying, Ligunas, Gloria Denise, Chin, Wei-Chun, Ni, Chih-Wen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7240061/
https://ncbi.nlm.nih.gov/pubmed/32462054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.04.020
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