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Impaired differentiation of human induced neural stem cells by TOR1A overexpression

DYT-TOR1A is the most common inherited dystonia caused by a three nucleotide (GAG) deletion (dE) in the TOR1A gene. Death early after birth and cortical anomalies of the full knockout in rodents underscore its developmental importance. We therefore explored the timed effects of TOR1A-wt and TOR1A-dE...

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Dettagli Bibliografici
Pubblicato in:Mol Biol Rep
Autori principali: Stengel, Felix, Vulinovic, Franca, Meier, Britta, Grütz, Karen, Klein, Christine, Capetian, Philipp
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer Netherlands 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239838/
https://ncbi.nlm.nih.gov/pubmed/32239467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-020-05390-x
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