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Biology of the somatotroph axis (after the pituitary)
Normal growth requires that pituitary-secreted growth hormone (GH) bind to its specific receptor and activate a complex signaling cascade, leaving to production of insulin-like growth factor-I (IGF-I), which, in turn, activates its own receptor (IGF1R). The GH receptor (GHR) is preformed as a dimer...
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| Publicado no: | Ann Endocrinol (Paris) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7239688/ https://ncbi.nlm.nih.gov/pubmed/28495324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ando.2017.04.002 |
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