Self-assembly behaviors and application of terphenyl-cored trimaltosides for membrane protein study: Impact of detergent hydrophobic group geometry on protein stability

Amphipathic agents are widely used in various fields including biomedical sciences. Micelle-forming detergents are particularly useful for in vitro membrane protein characterization. As many conventional detergents are limited in their ability to stabilize membrane proteins, it is necessary to devel...

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Veröffentlicht in:Chemistry
Hauptverfasser: Ehsan, Muhammad, Du, Yang, Mortensen, Jonas S., Hariharan, Parameswaran, Qu, Qianhui, Ghani, Lubna, Das, Manabendra, Grethen, Anne, Byrne, Bernadette, Skiniotis, Georgios, Keller, Sandro, Loland, Claus J., Guan, Lan, Kobilka, Brian K., Chae, Pil Seok
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7239454/
https://ncbi.nlm.nih.gov/pubmed/31243822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201902468
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